The study introduces flexocatalysis, a novel catalytic approach utilizing the flexoelectric effect in nanoscale SrTiO₃ to drive hydrogen production and organic pollutant degradation. Unlike piezocatalysis, flexocatalysis is not limited by symmetry constraints, enabling the use of centrosymmetric materials like SrTiO₃. The research involved comprehensive experimental assessments of nano SrTiO₃, including structural, surface, and catalytic performance evaluations. Results showed impressive hydrogen production rates and efficient organic pollutant degradation by STO nanoparticles under ultrasonic vibration. The study emphasizes the practical potential of flexocatalysis for greener energy generation and environmental cleanup. Nano SrTiO₃'s structural stability, recyclability, and performance consistency position it as a promising catalyst for future applications in energy and environmental management. By expanding the materials suitable for mechanically driven catalysis and enhancing understanding of electromechanical behavior at the nanoscale, this work contributes to the development of adaptable and efficient catalytic systems.