The article discusses the importance of optimizing the structure of the interface between a polymer electrolyte membrane (PEM) and catalyst layer (CL) in membrane electrode assembly (MEA) to enhance the performance of polymer electrolyte membrane fuel cells (PEMFCs). A method to generate nano or micro-sculptures on Nafion membranes using reactive ion etching (RIE) is proposed. By controlling the RIE process time, the dimensions of the surface sculptures can be adjusted, influencing the stacking structure of Pt/C particles and ionomer connectivity in the CL. The study found that MEAs with 400 nm high sculptures exhibited a remarkable 82.8% increase in power density compared to pristine Nafion membranes under low Pt loading and low relative humidity conditions. This surface modification approach using plasma treatment through RIE was effective in enhancing PEMFC performance, particularly in low humid and low catalyst conditions. The article also compares various methods for surface modifications of PEMs, highlighting the scalability and controllability of plasma treatment in creating surface sculptures to improve electrochemical performance in PEMFCs.