The chapter provides a comprehensive analysis of advancing low-temperature electrolysis methods for sustainable hydrogen production. It starts by outlining the significance and challenges of water splitting, followed by a detailed discussion on the electrochemical processes and key performance indicators involved. Various innovative strategies such as decoupled, hybrid, tandem, and microbial electrolysis cells, along with seawater electrolysis, are extensively reviewed, focusing on their operational principles and successful outcomes. The text also addresses the existing hurdles in these techniques and presents insights into their future prospects. By exploring these strategies, the chapter aims to drive progress in clean energy technologies and facilitate the shift towards a hydrogen-centric economy.