The Dalton Nuclear Institute at The University of Manchester plays a pivotal role in advancing nuclear research in the UK, spanning from fission to fusion, medical applications, and social sciences. Nuclear materials are indispensable for various sectors, facilitating energy production through fission reactors and potentially future fusion reactors, as well as enabling medical diagnoses and treatments. Nuclear fusion, with its green energy potential, could offer stable electricity and secondary applications like hydrogen production, contributing to a long-term low-carbon energy strategy. While faced with challenges, fusion research aims for net energy gain, materials resilience, tritium management, and regulatory frameworks for grid integration. Collaboration and training are key to achieving commercial fusion viability. Strategies for nuclear waste management are also being developed, illustrating the holistic approach of institutions like the Dalton Nuclear Institute in shaping a sustainable energy future.