Hydrogen trains are gaining momentum in reshaping the landscape of rail transportation in the United States with the potential to significantly reduce carbon emissions. However, this transition comes with a set of challenges that go beyond just introducing new trains. The recent APTA Rail Conference served as a platform for leaders from prominent companies like Jacobs, HDR, Ricardo LLC, and SBCTA to address the readiness and hurdles associated with hydrogen trains. Martin Schroeder from Jacobs highlighted the necessity of restructuring the entire railway network to accommodate hydrogen's unique characteristics like flammability and storage requirements. This restructuring involves significant changes in tunnels, refueling stations, and maintenance operations. Marcin Taraszkiewicz of HDR emphasized the need for adapting European-designed hydrogen trains to suit American rail regulations, environmental conditions, and rail classes. This shift requires the establishment of national standards and regulations tailored for hydrogen technology. SBCTA, through its FLIRT H2025 train project, is at the forefront of hydrogen rail transportation in the US. The agency is focusing on building custom infrastructure for maintenance and hydrogen refueling to support the operational needs of these advanced trains. Joy Buenaflor from SBCTA underscored the importance of comprehensive safety measures, personnel training, and updated ventilation systems for tunnels and depots to ensure the safe operation of hydrogen trains. The project involves integrating safety features like deflagration panels, gas detectors, and automatic shut-off systems designed specifically for managing hydrogen properties efficiently. Addressing tunnel safety remains a crucial aspect of hydrogen train operations. Leaders like Schroeder and Taraszkiewicz emphasized the significance of proper ventilation and educating emergency response teams on handling hydrogen-powered vehicles. Despite the challenges, the potential of hydrogen trains in decarbonizing American railroads is a promising step towards a cleaner and more sustainable transportation future.