This study focuses on aligning fluctuating offshore wind power with stable hydrogen demand through a demand-driven hydrogen supply chain optimization model. It compares two hydrogen production strategies, partial grid-connected and fully off-grid electrolysis, in Guangdong, China. Results show that off-grid electrolysis leads to higher transportation costs due to greater station concentration, while grid-connected electrolysis has a lower levelized cost of hydrogen (LCOH) and limited cost reduction potential. The study emphasizes the importance of optimizing hydrogen supply chains to meet demand and reduce costs, especially in the context of sustainable energy transition and decarbonization goals. By considering the impact of different production strategies on the overall supply chain, the research provides valuable insights for the future development of hydrogen as a clean energy carrier, showcasing the potential for cost savings and carbon emissions reduction in the long term.